IL 2 signaling pathway
| PAG Title | IL 2 signaling pathway |
| PAG ID | WIG000354 |
| Type | P |
| Source Link |  MSigDB |
| Publication Reference | NA |
| PAG Description | Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 Receptors are found on activated B-Cells, LPS treated Monocytes, and many T cells. The receptor is formed from three chains alpha (CD25), beta (CD122), and gamma (CD132). Primary signaling is through the JAK/Stat pathway and MAPKs. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 6,045 |
| Information Content | Rich |
| Other IDs | M7747 |
| Base PAG ID | WIG000354 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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