Loading...

IL 2 signaling pathway

PAG Title IL 2 signaling pathway
PAG ID WIG000354
Type P
Source Link MSigDB
Publication Reference NA
PAG Description Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 Receptors are found on activated B-Cells, LPS treated Monocytes, and many T cells. The receptor is formed from three chains alpha (CD25), beta (CD122), and gamma (CD132). Primary signaling is through the JAK/Stat pathway and MAPKs.
Species Homo sapiens
nCoCo Score 6,045
Base PAG ID WIG000354
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
Related PAGs